Mulungu (Erythrina mulungu ), native to South America, is traditionally valued for its benefits to the nervous system.

 The main tetracyclic alkaloids , such as erythravine and (+)-11-α-hydroxy-erythravine , are characteristic components of the genus Erythrina and have been identified specifically in Mulungu. (See ethnobotanical record)

 Erythravine: This alkaloid has demonstrated anxiolytic effects in animal models and can also modulate nicotinic receptors, as indicated by research on neuronal activity. ( See details .)

 Preclinical studies: Crude extracts of Erythrina mulungu and some of its isolated alkaloids have shown anxiolytic activity in animal models, with measurable effects comparable to those of drugs such as diazepam. ( See publication )

 Recent review (2025): A literature review indicates that various alkaloids of the genus Erythrina, including those from Mulungu, may exert modulating effects on the central nervous system, such as anxiolytic, sedative, and anticonvulsant effects. ( See review )

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